Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44552
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44552
Synonyms:
3-(4-Chloro-phenyl)-9-methyl-2H-1-thia-4,4a-diaza-9-azonia-fluorene | 3-(4-chlorophenyl)-10-methyl-2H-[1,3,4]thiadiazino[3,2-a]benzimidazol-10-ium;bromide | MLS000552347 | SMR000177119 | cid_11958731
Type:
Small organic molecule
Emp. Form.:
C16H13ClN3S
Mol. Mass.:
314.812
SMILES:
C[n+]1c2SCC(=Nn2c2ccccc12)c1ccc(Cl)cc1 |c:5|
Structure:
Search PDB for entries with ligand similarity: