Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM40727
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM40727
Synonyms:
MLS000537135 | N'-(4-fluorobenzylidene)-2-(2-furyl)-4-quinolinecarbohydrazide | N-[(4-fluorobenzylidene)amino]-2-(2-furyl)cinchoninamide | N-[(4-fluorophenyl)methylideneamino]-2-(2-furanyl)-4-quinolinecarboxamide | N-[(4-fluorophenyl)methylideneamino]-2-(furan-2-yl)quinoline-4-carboxamide | SMR000159894 | cid_1226487
Type:
Small organic molecule
Emp. Form.:
C21H14FN3O2
Mol. Mass.:
359.3532
SMILES:
Fc1ccc(C=NNC(=O)c2cc(nc3ccccc23)-c2ccco2)cc1 |w:6.6|
Structure:
Search PDB for entries with ligand similarity: