Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41638
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
>50000±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41638
Synonyms:
3-(3-Methyl-benzoylamino)-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid cyclohexylamide | MLS000074250 | N-cyclohexyl-3-(m-toluoylamino)-9-azabicyclo[3.3.1]nonane-9-carboxamide | N-cyclohexyl-3-[(3-methylbenzoyl)amino]-9-azabicyclo[3.3.1]nonane-9-carboxamide | N-cyclohexyl-3-[(3-methylphenyl)carbonylamino]-9-azabicyclo[3.3.1]nonane-9-carboxamide | N-cyclohexyl-3-[[(3-methylphenyl)-oxomethyl]amino]-9-azabicyclo[3.3.1]nonane-9-carboxamide | SMR000006243 | cid_647078
Type:
Small organic molecule
Emp. Form.:
C23H33N3O2
Mol. Mass.:
383.527
SMILES:
[H]C12CCCC([H])(CC(C1)NC(=O)c1cccc(C)c1)N2C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: