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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM37140
Substrate
n/a
Meas. Tech.
Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
IC50
2951±n/a nM
Citation
 PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay (2008)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM37140
Synonyms:
MLS000096729 | N-[3-chloro-4-[4-(1-oxobutyl)-1-piperazinyl]phenyl]-2-benzofurancarboxamide | N-[4-(4-butanoylpiperazin-1-yl)-3-chloranyl-phenyl]-1-benzofuran-2-carboxamide | N-[4-(4-butanoylpiperazin-1-yl)-3-chlorophenyl]-1-benzofuran-2-carboxamide | N-[4-(4-butyryl-1-piperazinyl)-3-chlorophenyl]-1-benzofuran-2-carboxamide | N-[4-(4-butyrylpiperazino)-3-chloro-phenyl]coumarilamide | SMR000074009 | cid_2944643
Type:
Small organic molecule
Emp. Form.:
C23H24ClN3O3
Mol. Mass.:
425.908
SMILES:
CCCC(=O)N1CCN(CC1)c1ccc(NC(=O)c2cc3ccccc3o2)cc1Cl
Structure:
Search PDB for entries with ligand similarity: