Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32259
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
12690±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32259
Synonyms:
4-(6-methyl-5-imidazo[2,1-b]thiazolyl)-N-(4-methyl-2-pyridinyl)-2-thiazolamine | 4-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)-N-(4-methylpyridin-2-yl)-1,3-thiazol-2-amine | MLS000034327 | SMR000010233 | [4-(6-Methyl-imidazo[2,1-b]thiazol-5-yl)-thiazol-2-yl]-(4-methyl-pyridin-2-yl)-amine | [4-(6-methylimidazo[2,1-b]thiazol-5-yl)thiazol-2-yl]-(4-methyl-2-pyridyl)amine | cid_644740
Type:
Small organic molecule
Emp. Form.:
C15H13N5S2
Mol. Mass.:
327.427
SMILES:
Cc1nc2sccn2c1-c1csc(Nc2cc(C)ccn2)n1
Structure:
Search PDB for entries with ligand similarity: