Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM33160
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
12560±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM33160
Synonyms:
1-benzyl-3-chloro-4-(2-hydroxy-5-methyl-anilino)-3-pyrroline-2,5-quinone | 1-benzyl-3-chloro-4-(2-hydroxy-5-methylanilino)pyrrole-2,5-dione | 1-benzyl-3-chloro-4-[(2-hydroxy-5-methylphenyl)amino]-1H-pyrrole-2,5-dione | 3-chloranyl-4-[(5-methyl-2-oxidanyl-phenyl)amino]-1-(phenylmethyl)pyrrole-2,5-dione | 3-chloro-4-(2-hydroxy-5-methylanilino)-1-(phenylmethyl)pyrrole-2,5-dione | MLS000626713 | SMR000299098 | cid_731393
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O3
Mol. Mass.:
342.776
SMILES:
Cc1ccc(O)c(NC2=C(Cl)C(=O)N(Cc3ccccc3)C2=O)c1 |c:8|
Structure:
Search PDB for entries with ligand similarity: