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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM46305
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
20950±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM46305
Synonyms:
MLS000589586 | N-[(4-bromophenyl)methylideneamino]-7-chloranyl-quinolin-4-amine | N-[(4-bromophenyl)methylideneamino]-7-chloro-4-quinolinamine | N-[(4-bromophenyl)methylideneamino]-7-chloroquinolin-4-amine | N-[1-(4-Bromo-phenyl)-meth-(E)-ylidene]-N'-(7-chloro-quinolin-4-yl)-hydrazine | SMR000213031 | [(4-bromobenzylidene)amino]-(7-chloro-4-quinolyl)amine | cid_3715689
Type:
Small organic molecule
Emp. Form.:
C16H11BrClN3
Mol. Mass.:
360.636
SMILES:
Clc1ccc2c(ccnc2c1)N=NCc1ccc(Br)cc1 |w:11.12|
Structure:
Search PDB for entries with ligand similarity: