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Target
Bcl-2-like protein 2
Ligand
BDBM32265
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
2200±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32265
Synonyms:
4-(3-ethoxypropylamino)-6,7-dimethoxy-1H-quinazoline-2-thione | 4-[(3-ethoxypropyl)amino]-6,7-dimethoxyquinazoline-2(1H)-thione | MLS000045007 | SMR000026611 | cid_3237310
Type:
Small organic molecule
Emp. Form.:
C15H21N3O3S
Mol. Mass.:
323.411
SMILES:
CCOCCCNc1[nH]c(=S)nc2cc(OC)c(OC)cc12
Structure:
Search PDB for entries with ligand similarity: