Reaction Details Report a problem with these data
Target
Bcl-2-like protein 2
Ligand
BDBM33076
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
28260±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33076
Synonyms:
2,3-bis(2-furanyl)-6-methoxyquinoxaline | 2,3-bis(2-furyl)-6-methoxy-quinoxaline | 2,3-bis(furan-2-yl)-6-methoxy-quinoxaline | 2,3-bis(furan-2-yl)-6-methoxyquinoxaline | 2,3-di-2-furyl-6-methoxyquinoxaline | MLS000532354 | SMR000137313 | cid_762708
Type:
Small organic molecule
Emp. Form.:
C17H12N2O3
Mol. Mass.:
292.2888
SMILES:
COc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: