Reaction Details Report a problem with these data
Target
Bcl-2-like protein 2
Ligand
BDBM33089
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
3960±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33089
Synonyms:
(3-methyl-4-pyrrolidino-phenyl)amine;hydrochloride | 3-methyl-4-(1-pyrrolidinyl)aniline;hydrochloride | 3-methyl-4-pyrrolidin-1-yl-aniline;hydrochloride | 3-methyl-4-pyrrolidin-1-ylaniline;hydrochloride | MLS000566003 | SMR000153134 | cid_109673
Type:
Small organic molecule
Emp. Form.:
C11H16N2
Mol. Mass.:
176.2581
SMILES:
Cc1cc(N)ccc1N1CCCC1
Structure:
Search PDB for entries with ligand similarity: