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Target
Bcl-2-like protein 2
Ligand
BDBM33126
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
3490±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33126
Synonyms:
MLS000392298 | N-[3-[(1,1-diketothiolan-3-yl)amino]-1,4-diketo-2-naphthyl]acetamide | N-[3-[(1,1-dioxo-3-thiolanyl)amino]-1,4-dioxo-2-naphthalenyl]acetamide | N-[3-[(1,1-dioxothiolan-3-yl)amino]-1,4-dioxonaphthalen-2-yl]acetamide | N-[3-[[1,1-bis(oxidanylidene)thiolan-3-yl]amino]-1,4-bis(oxidanylidene)naphthalen-2-yl]ethanamide | SMR000261267 | cid_3661963
Type:
Small organic molecule
Emp. Form.:
C16H16N2O5S
Mol. Mass.:
348.374
SMILES:
CC(=O)NC1=C(NC2CCS(=O)(=O)C2)C(=O)c2ccccc2C1=O |c:4|
Structure:
Search PDB for entries with ligand similarity: