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Target
Bcl-2-like protein 2
Ligand
BDBM33127
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
4340±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33127
Synonyms:
MLS000392290 | N-[3-(3-chloro-4-methyl-anilino)-1,4-diketo-2-naphthyl]benzamide | N-[3-(3-chloro-4-methylanilino)-1,4-dioxo-2-naphthalenyl]benzamide | N-[3-(3-chloro-4-methylanilino)-1,4-dioxonaphthalen-2-yl]benzamide | N-[3-[(3-chloranyl-4-methyl-phenyl)amino]-1,4-bis(oxidanylidene)naphthalen-2-yl]benzamide | SMR000261286 | cid_5082182
Type:
Small organic molecule
Emp. Form.:
C24H17ClN2O3
Mol. Mass.:
416.856
SMILES:
Cc1ccc(NC2=C(NC(=O)c3ccccc3)C(=O)c3ccccc3C2=O)cc1Cl |c:6|
Structure:
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