Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43207
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
5803±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43207
Synonyms:
2-[(2,6-dichlorobenzyl)amino]-3-methyl-butyric acid | 2-[(2,6-dichlorophenyl)methylamino]-3-methylbutanoic acid | 2-[[2,6-bis(chloranyl)phenyl]methylamino]-3-methyl-butanoic acid | MLS000095936 | N-(2,6-dichlorobenzyl)valine | SMR000031484 | cid_3237092
Type:
Small organic molecule
Emp. Form.:
C12H15Cl2NO2
Mol. Mass.:
276.159
SMILES:
CC(C)C(NCc1c(Cl)cccc1Cl)C(O)=O
Structure:
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