Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46327
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
93070±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46327
Synonyms:
(2E)-2-(3-pyridinylmethylidene)-1-benzothiophen-3-one | (2E)-2-(3-pyridylmethylene)benzothiophen-3-one | (2E)-2-(pyridin-3-ylmethylidene)-1-benzothiophen-3-one | 2-Pyridin-3-ylmethylene-benzo[b]thiophen-3-one | MLS000566847 | SMR000176243 | cid_1721018
Type:
Small organic molecule
Emp. Form.:
C14H9NOS
Mol. Mass.:
239.292
SMILES:
O=C1\C(Sc2ccccc12)=C/c1cccnc1
Structure:
Search PDB for entries with ligand similarity: