Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM46332
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
EC50
3398±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM46332
Synonyms:
4-(4-acetylanilino)-2-quinazolinecarboxylic acid ethyl ester | 4-(4-acetylanilino)quinazoline-2-carboxylic acid ethyl ester | MLS000766761 | SMR000339657 | cid_731991 | ethyl 4-(4-acetylanilino)quinazoline-2-carboxylate | ethyl 4-[(4-acetylphenyl)amino]quinazoline-2-carboxylate | ethyl 4-[(4-ethanoylphenyl)amino]quinazoline-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H17N3O3
Mol. Mass.:
335.3566
SMILES:
CCOC(=O)c1nc(Nc2ccc(cc2)C(C)=O)c2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: