Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM36863
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
3028±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM36863
Synonyms:
4-(Cyclohexylmethyl-sulfamoyl)-N-thiazol-2-yl-benzamide | 4-(cyclohexylmethylsulfamoyl)-N-(1,3-thiazol-2-yl)benzamide | 4-(cyclohexylmethylsulfamoyl)-N-(2-thiazolyl)benzamide | 4-(cyclohexylmethylsulfamoyl)-N-thiazol-2-yl-benzamide | MLS000026799 | SMR000007571 | cid_652627
Type:
Small organic molecule
Emp. Form.:
C17H21N3O3S2
Mol. Mass.:
379.497
SMILES:
O=C(Nc1nccs1)c1ccc(cc1)S(=O)(=O)NCC1CCCCC1
Structure:
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