Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46368
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
4479±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46368
Synonyms:
4-(1,3-benzothiazol-2-yl)-N-(2,6-dimethylphenyl)-1-piperazinecarboxamide | 4-(1,3-benzothiazol-2-yl)-N-(2,6-dimethylphenyl)piperazine-1-carboxamide | MLS000520588 | SMR000130999 | cid_9550816
Type:
Small organic molecule
Emp. Form.:
C20H22N4OS
Mol. Mass.:
366.48
SMILES:
Cc1cccc(C)c1NC(=O)N1CCN(CC1)c1nc2ccccc2s1
Structure:
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