Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46370
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
3184±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46370
Synonyms:
2-(4-bromanyl-3,5-dimethyl-phenoxy)-N-pyridin-4-yl-ethanamide | 2-(4-bromo-3,5-dimethyl-phenoxy)-N-(4-pyridyl)acetamide | 2-(4-bromo-3,5-dimethylphenoxy)-N-4-pyridinylacetamide | 2-(4-bromo-3,5-dimethylphenoxy)-N-pyridin-4-ylacetamide | MLS000534662 | SMR000142079 | cid_803320
Type:
Small organic molecule
Emp. Form.:
C15H15BrN2O2
Mol. Mass.:
335.196
SMILES:
Cc1cc(OCC(=O)Nc2ccncc2)cc(C)c1Br
Structure:
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