Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46377
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
2066±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46377
Synonyms:
4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazonoyl)-2-methoxyphenyl methyl carbonate | MLS000545073 | SMR000161216 | [4-[[2-[(2-bromophenyl)methylsulfanyl]ethanoylhydrazinylidene]methyl]-2-methoxy-phenyl] methyl carbonate | [4-[[[2-[(2-bromophenyl)methylsulfanyl]acetyl]hydrazinylidene]methyl]-2-methoxyphenyl] methyl carbonate | carbonic acid [4-[[[2-[(2-bromobenzyl)thio]acetyl]hydrazono]methyl]-2-methoxy-phenyl] methyl ester | carbonic acid [4-[[[2-[(2-bromophenyl)methylthio]-1-oxoethyl]hydrazinylidene]methyl]-2-methoxyphenyl] methyl ester | cid_987778
Type:
Small organic molecule
Emp. Form.:
C19H19BrN2O5S
Mol. Mass.:
467.334
SMILES:
COC(=O)Oc1ccc(C=NNC(=O)CSCc2ccccc2Br)cc1OC |w:10.10|
Structure:
Search PDB for entries with ligand similarity: