Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46382
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
6762±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46382
Synonyms:
2-(4-Chloro-benzyl)-5-phenyl-2H-pyrazol-3-ylamine | 2-[(4-chlorophenyl)methyl]-5-phenyl-3-pyrazolamine | 2-[(4-chlorophenyl)methyl]-5-phenyl-pyrazol-3-amine | 2-[(4-chlorophenyl)methyl]-5-phenylpyrazol-3-amine | MLS000562289 | SMR000174888 | [2-(4-chlorobenzyl)-5-phenyl-pyrazol-3-yl]amine | cid_814441
Type:
Small organic molecule
Emp. Form.:
C16H14ClN3
Mol. Mass.:
283.755
SMILES:
Nc1cc(nn1Cc1ccc(Cl)cc1)-c1ccccc1
Structure:
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