Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46419
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
6337±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46419
Synonyms:
MLS000706672 | N-[4-[2-[(5-chloranylpyridin-2-yl)amino]-1,3-thiazol-4-yl]phenyl]ethanamide | N-[4-[2-[(5-chloro-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide | N-[4-[2-[(5-chloro-2-pyridyl)amino]thiazol-4-yl]phenyl]acetamide | N-[4-[2-[(5-chloropyridin-2-yl)amino]-1,3-thiazol-4-yl]phenyl]acetamide | SMR000288124 | cid_972726
Type:
Small organic molecule
Emp. Form.:
C16H13ClN4OS
Mol. Mass.:
344.819
SMILES:
CC(=O)Nc1ccc(cc1)-c1csc(Nc2ccc(Cl)cn2)n1
Structure:
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