Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46427
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
6367±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46427
Synonyms:
2-(3,4-dimethoxyphenyl)-N-(3-methylsulfanylphenyl)acetamide | 2-(3,4-dimethoxyphenyl)-N-(3-methylsulfanylphenyl)ethanamide | 2-(3,4-dimethoxyphenyl)-N-[3-(methylthio)phenyl]acetamide | MLS000772862 | SMR000377415 | cid_4879668
Type:
Small organic molecule
Emp. Form.:
C17H19NO3S
Mol. Mass.:
317.403
SMILES:
COc1ccc(CC(=O)Nc2cccc(SC)c2)cc1OC
Structure:
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