Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43510
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43510
Synonyms:
3-[oxo(1-pyrrolidinyl)methyl]-5-(phenylmethyl)-6-benzo[b][1,4]benzothiazepinone | 5-(phenylmethyl)-3-pyrrolidin-1-ylcarbonyl-benzo[b][1,4]benzothiazepin-6-one | 5-benzyl-3-(pyrrolidine-1-carbonyl)benzo[b][1,4]benzothiazepin-6-one | MLS000521016 | SMR000131425 | cid_5142274
Type:
Small organic molecule
Emp. Form.:
C25H22N2O2S
Mol. Mass.:
414.519
SMILES:
O=C(N1CCCC1)c1ccc2Sc3ccccc3C(=O)N(Cc3ccccc3)c2c1
Structure:
Search PDB for entries with ligand similarity: