Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43512
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43512
Synonyms:
3-(3,4-dimethylphenyl)-4-keto-phthalazine-1-carboxylic acid | 3-(3,4-dimethylphenyl)-4-oxidanylidene-phthalazine-1-carboxylic acid | 3-(3,4-dimethylphenyl)-4-oxo-1-phthalazinecarboxylic acid | 3-(3,4-dimethylphenyl)-4-oxo-3,4-dihydro-1-phthalazinecarboxylic acid | 3-(3,4-dimethylphenyl)-4-oxophthalazine-1-carboxylic acid | MLS000544969 | SMR000126726 | cid_3743088
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3
Mol. Mass.:
294.3047
SMILES:
Cc1ccc(cc1C)-n1nc(C(O)=O)c2ccccc2c1=O
Structure:
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