Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43515
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43515
Synonyms:
5-amino-3-(3,4,5-triethoxyphenyl)-1,2-oxazole-4-carbonitrile | 5-amino-3-(3,4,5-triethoxyphenyl)-4-isoxazolecarbonitrile | 5-amino-3-(3,4,5-triethoxyphenyl)isoxazole-4-carbonitrile | 5-azanyl-3-(3,4,5-triethoxyphenyl)-1,2-oxazole-4-carbonitrile | MLS000520399 | SMR000130810 | cid_6618836
Type:
Small organic molecule
Emp. Form.:
C16H19N3O4
Mol. Mass.:
317.3398
SMILES:
CCOc1cc(cc(OCC)c1OCC)-c1noc(N)c1C#N
Structure:
Search PDB for entries with ligand similarity: