Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43536
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43536
Synonyms:
(7-chloroquinazolin-4-yl)-o-anisyl-amine | 7-chloranyl-N-[(2-methoxyphenyl)methyl]quinazolin-4-amine | 7-chloro-N-(2-methoxybenzyl)-4-quinazolinamine | 7-chloro-N-[(2-methoxyphenyl)methyl]-4-quinazolinamine | 7-chloro-N-[(2-methoxyphenyl)methyl]quinazolin-4-amine | MLS000721157 | SMR000335342 | cid_1490540
Type:
Small organic molecule
Emp. Form.:
C16H14ClN3O
Mol. Mass.:
299.755
SMILES:
COc1ccccc1CNc1ncnc2cc(Cl)ccc12
Structure:
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