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Target
Transitional endoplasmic reticulum ATPase
Ligand
BDBM46553
Substrate
n/a
Meas. Tech.
Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase
IC50
>50000±n/a nM
Citation
 PubChem, PC Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase PubChem Bioassay (2009)[AID] 
Target
Name:
Transitional endoplasmic reticulum ATPase
Synonyms:
TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein
Type:
Enzyme
Mol. Mass.:
89300.63
Organism:
Homo sapiens (Human)
Description:
P55072
Residue:
806
Sequence:
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG
  
Inhibitor
Name:
BDBM46553
Synonyms:
(6Z)-6-(4-anilino-6-methyl-1H-pyrimidin-2-ylidene)-1-cyclohexa-2,4-dienone | (6Z)-6-(4-anilino-6-methyl-1H-pyrimidin-2-ylidene)cyclohexa-2,4-dien-1-one | (6Z)-6-(6-methyl-4-phenylazanyl-1H-pyrimidin-2-ylidene)cyclohexa-2,4-dien-1-one | 2-(4-anilino-6-methyl-2-pyrimidinyl)phenol | MLS000062061 | SMR000070057 | cid_5413643
Type:
Small organic molecule
Emp. Form.:
C17H15N3O
Mol. Mass.:
277.3205
SMILES:
Cc1cc(Nc2ccccc2)nc(n1)-c1ccccc1O
Structure:
Search PDB for entries with ligand similarity: