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Target
Transitional endoplasmic reticulum ATPase
Ligand
BDBM46568
Substrate
n/a
Meas. Tech.
Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase
IC50
>50000±n/a nM
Citation
 PubChem, PC Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase PubChem Bioassay (2009)[AID] 
Target
Name:
Transitional endoplasmic reticulum ATPase
Synonyms:
TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein
Type:
Enzyme
Mol. Mass.:
89300.63
Organism:
Homo sapiens (Human)
Description:
P55072
Residue:
806
Sequence:
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG
  
Inhibitor
Name:
BDBM46568
Synonyms:
(2Z)-7-chloranyl-2-[(2E)-1-chloranyl-2-(3-chloranyl-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)ethylidene]-1H-quinazolin-4-one | (2Z)-7-chloro-2-[(2E)-1-chloro-2-(3-chloro-6-keto-cyclohexa-2,4-dien-1-ylidene)ethylidene]-1H-quinazolin-4-one | (2Z)-7-chloro-2-[(2E)-1-chloro-2-(3-chloro-6-oxo-1-cyclohexa-2,4-dienylidene)ethylidene]-1H-quinazolin-4-one | (2Z)-7-chloro-2-[(2E)-1-chloro-2-(3-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)ethylidene]-1H-quinazolin-4-one | MLS000394715 | SMR000242822 | cid_15945307
Type:
Small organic molecule
Emp. Form.:
C16H9Cl3N2O2
Mol. Mass.:
367.614
SMILES:
Oc1ccc(Cl)cc1C=C(Cl)c1nc2cc(Cl)ccc2c(=O)[nH]1 |w:9.10|
Structure:
Search PDB for entries with ligand similarity: