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Target
Mannose-6-phosphate isomerase
Ligand
BDBM46636
Substrate
n/a
Meas. Tech.
Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
2140±n/a nM
Citation
 PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2010)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM46636
Synonyms:
2-[4-[chloranyl-bis(fluoranyl)methoxy]phenyl]-4,6-dinitro-1,2-benzothiazol-3-one | 2-[4-[chloro(difluoro)methoxy]phenyl]-4,6-dinitro-1,2-benzothiazol-3-one | MLS-0315788.0001 | cid_4362535
Type:
Small organic molecule
Emp. Form.:
C14H6ClF2N3O6S
Mol. Mass.:
417.729
SMILES:
[O-][N+](=O)c1cc([N+]([O-])=O)c2c(c1)sn(-c1ccc(OC(F)(F)Cl)cc1)c2=O
Structure:
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