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Target
Procathepsin L
Ligand
BDBM41100
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
2059.01±295.76602 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41100
Synonyms:
2-[cyano-[4-(dimethylamino)-6-(methylthio)-1,3,5-triazin-2-yl]amino]propanedioic acid diethyl ester | 2-[cyano-[4-(dimethylamino)-6-(methylthio)-s-triazin-2-yl]amino]malonic acid diethyl ester | MLS000080173 | SMR000039053 | cid_658152 | diethyl 2-[cyano-[4-(dimethylamino)-6-methylsulfanyl-1,3,5-triazin-2-yl]amino]propanedioate
Type:
Small organic molecule
Emp. Form.:
C14H20N6O4S
Mol. Mass.:
368.411
SMILES:
CCOC(=O)C(N(C#N)c1nc(SC)nc(n1)N(C)C)C(=O)OCC
Structure:
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