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Target
Procathepsin L
Ligand
BDBM41151
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
15827.60667±1040.84570 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41151
Synonyms:
MLS000055134 | N-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]methyl]-2-fluoranyl-N-(furan-2-ylmethyl)benzenesulfonamide | N-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]methyl]-2-fluoro-N-(2-furanylmethyl)benzenesulfonamide | N-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]methyl]-2-fluoro-N-(2-furfuryl)benzenesulfonamide | N-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]methyl]-2-fluoro-N-(furan-2-ylmethyl)benzenesulfonamide | SMR000066760 | cid_2110790
Type:
Small organic molecule
Emp. Form.:
C20H15BrFN3O4S
Mol. Mass.:
492.318
SMILES:
Fc1ccccc1S(=O)(=O)N(Cc1ccco1)Cc1nnc(o1)-c1ccccc1Br
Structure:
Search PDB for entries with ligand similarity: