Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM34346
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
65900±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM34346
Synonyms:
2-(4-methyl-2-pyrimidinyl)-1,2-benzothiazol-3-one | 2-(4-methylpyrimidin-2-yl)-1,2-benzothiazol-3-one | MLS000035998 | SMR000062532 | cid_2408437
Type:
Small organic molecule
Emp. Form.:
C12H9N3OS
Mol. Mass.:
243.284
SMILES:
Cc1ccnc(n1)-n1sc2ccccc2c1=O
Structure:
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