Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46642
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46642
Synonyms:
MLS-0246017.0001 | N-[1,3-benzothiazol-2-yl(phenyl)phosphoryl]-4-methyl-aniline | N-[1,3-benzothiazol-2-yl(phenyl)phosphoryl]-4-methylaniline | [1,3-benzothiazol-2-yl(phenyl)phosphoryl]-(p-tolyl)amine | cid_4829397
Type:
Small organic molecule
Emp. Form.:
C20H17N2OPS
Mol. Mass.:
364.401
SMILES:
Cc1ccc(NP(=O)(c2nc3ccccc3s2)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: