Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46647
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46647
Synonyms:
2-(5-morpholin-4-ylsulfonyl-2-piperidin-1-yl-phenyl)-1,2-benzothiazol-3-one | 2-(5-morpholin-4-ylsulfonyl-2-piperidin-1-ylphenyl)-1,2-benzothiazol-3-one | 2-(5-morpholinosulfonyl-2-piperidino-phenyl)-1,2-benzothiazol-3-one | 2-[5-(4-morpholinylsulfonyl)-2-(1-piperidinyl)phenyl]-1,2-benzothiazol-3-one | MLS-0315796.0001 | cid_2327939
Type:
Small organic molecule
Emp. Form.:
C22H25N3O4S2
Mol. Mass.:
459.582
SMILES:
O=c1n(sc2ccccc12)-c1cc(ccc1N1CCCCC1)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: