Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46651
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46651
Synonyms:
2-[6-(difluoromethylsulfanyl)-1,3-benzothiazol-2-yl]-1,2-benzothiazol-3-one | 2-[6-(difluoromethylthio)-1,3-benzothiazol-2-yl]-1,2-benzothiazol-3-one | 2-[6-[bis(fluoranyl)methylsulfanyl]-1,3-benzothiazol-2-yl]-1,2-benzothiazol-3-one | MLS-0315800.0001 | cid_2328642
Type:
Small organic molecule
Emp. Form.:
C15H8F2N2OS3
Mol. Mass.:
366.429
SMILES:
FC(F)Sc1ccc2nc(sc2c1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: