Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46666
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46666
Synonyms:
5-(4-methoxyphenyl)-1H-1,2,4-triazol-3-amine | MLS-0070117.0001 | [5-(4-methoxyphenyl)-1H-1,2,4-triazol-3-yl]amine | cid_781002
Type:
Small organic molecule
Emp. Form.:
C9H10N4O
Mol. Mass.:
190.2019
SMILES:
COc1ccc(cc1)-c1nnc(N)[nH]1
Structure:
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