Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46678
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46678
Synonyms:
2-[(4-chloranyl-1,2,3-dithiazol-5-ylidene)amino]-N-(4-chlorophenyl)aniline | 2-[(4-chloro-5-dithiazolylidene)amino]-N-(4-chlorophenyl)aniline | 2-[(4-chlorodithiazol-5-ylidene)amino]-N-(4-chlorophenyl)aniline | MLS-0390821.0001 | [2-[(4-chlorodithiazol-5-ylidene)amino]phenyl]-(4-chlorophenyl)amine | cid_620131
Type:
Small organic molecule
Emp. Form.:
C14H9Cl2N3S2
Mol. Mass.:
354.277
SMILES:
Clc1nss\c1=N\c1ccccc1Nc1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: