Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM34737
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM34737
Synonyms:
2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | 2-(4-methylphenyl)-1,2-benzothiazol-3-one | 2-(p-tolyl)-1,2-benzothiazol-3-one | MLS000583746 | SMR000200989 | acs.jmedchem.1c00409_ST.174 | cid_935415
Type:
Small organic molecule
Emp. Form.:
C14H11NOS
Mol. Mass.:
241.308
SMILES:
Cc1ccc(cc1)-n1sc2ccccc2c1=O
Structure:
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