Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46702
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
88600±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46702
Synonyms:
(4-chlorodithiazol-5-ylidene)-(3,4-dichlorophenyl)amine | 4-chloranyl-N-(3,4-dichlorophenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(3,4-dichlorophenyl)-5-dithiazolimine | 4-chloro-N-(3,4-dichlorophenyl)dithiazol-5-imine | MLS-0390890.0001 | cid_2769041
Type:
Small organic molecule
Emp. Form.:
C8H3Cl3N2S2
Mol. Mass.:
297.612
SMILES:
Clc1nss\c1=N/c1ccc(Cl)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: