Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM46640
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
1960±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM46640
Synonyms:
2-phenylnaphtho[2,3-g][1,2]benzothiazole-3,6,11-trione | MLS-0315791.0001 | cid_4695672
Type:
Small organic molecule
Emp. Form.:
C21H11NO3S
Mol. Mass.:
357.382
SMILES:
O=C1c2ccccc2C(=O)c2c1ccc1c2sn(-c2ccccc2)c1=O
Structure:
Search PDB for entries with ligand similarity: