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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM47507
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen assay for S1P4 agonists: Cell-based dose response high throughput screening assay to identify agonists of the Sphingosine 1-Phosphate Receptor 1 (S1P1)
EC50
>5530±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen assay for S1P4 agonists: Cell-based dose response high throughput screening assay to identify agonists of the Sphingosine 1-Phosphate Receptor 1 (S1P1) PubChem Bioassay (2010)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM47507
Synonyms:
4-[2-(6-ethoxy-2-quinolinyl)ethenyl]-N,N-dipropylaniline | 4-[2-(6-ethoxyquinolin-2-yl)ethenyl]-N,N-dipropyl-aniline | 4-[2-(6-ethoxyquinolin-2-yl)ethenyl]-N,N-dipropylaniline | MLS000766163 | SMR000528639 | [4-[2-(6-ethoxy-2-quinolyl)vinyl]phenyl]-dipropyl-amine | cid_289688
Type:
Small organic molecule
Emp. Form.:
C25H30N2O
Mol. Mass.:
374.5185
SMILES:
CCCN(CCC)c1ccc(C=Cc2ccc3cc(OCC)ccc3n2)cc1
Structure:
Search PDB for entries with ligand similarity: