Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM39554
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
50780±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM39554
Synonyms:
2-(2-furanylmethylamino)-10-pyridazino[6,1-b]quinazolinone | 2-(2-furfurylamino)pyridazino[6,1-b]quinazolin-10-one | 2-(furan-2-ylmethylamino)pyridazino[6,1-b]quinazolin-10-one | 2-[(2-furylmethyl)amino]-10H-pyridazino[6,1-b]quinazolin-10-one | MLS000094230 | SMR000029820 | cid_3243853
Type:
Small organic molecule
Emp. Form.:
C16H12N4O2
Mol. Mass.:
292.2921
SMILES:
O=c1c2ccccc2nc2ccc(NCc3ccco3)nn12
Structure:
Search PDB for entries with ligand similarity: