Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47561
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
2403±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47561
Synonyms:
1-[2-(3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]-1H-indole-6-carbonitrile | 1-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-keto-ethyl]indole-6-carbonitrile | 1-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxidanylidene-ethyl]indole-6-carbonitrile | 1-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]-6-indolecarbonitrile | 1-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]indole-6-carbonitrile | MLS000065048 | SMR000078417 | cid_974003
Type:
Small organic molecule
Emp. Form.:
C20H17N3O
Mol. Mass.:
315.3685
SMILES:
O=C(Cn1ccc2ccc(cc12)C#N)N1CCCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: