Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47622
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
49250±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47622
Synonyms:
4-(3-bromophenyl)-6-(2-furanyl)-2-oxo-1H-pyridine-3-carbonitrile | 4-(3-bromophenyl)-6-(2-furyl)-2-keto-1H-pyridine-3-carbonitrile | 4-(3-bromophenyl)-6-(2-furyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile | 4-(3-bromophenyl)-6-(furan-2-yl)-2-oxidanylidene-1H-pyridine-3-carbonitrile | 4-(3-bromophenyl)-6-(furan-2-yl)-2-oxo-1H-pyridine-3-carbonitrile | MLS000690791 | SMR000301247 | cid_5213229
Type:
Small organic molecule
Emp. Form.:
C16H9BrN2O2
Mol. Mass.:
341.159
SMILES:
Brc1cccc(c1)-c1cc([nH]c(=O)c1C#N)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: