Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47625
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
7506±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47625
Synonyms:
1-(7-methoxy-4-methyl-2-quinazolinyl)-2-(4-methylphenyl)sulfonylguanidine | 1-(7-methoxy-4-methyl-quinazolin-2-yl)-2-(4-methylphenyl)sulfonyl-guanidine | 1-(7-methoxy-4-methyl-quinazolin-2-yl)-2-tosyl-guanidine | 1-(7-methoxy-4-methylquinazolin-2-yl)-2-(4-methylphenyl)sulfonylguanidine | MLS000676718 | N-{amino[(7-methoxy-4-methyl-2-quinazolinyl)amino]methylene}-4-methylbenzenesulfonamide | SMR000298367 | cid_9586642
Type:
Small organic molecule
Emp. Form.:
C18H19N5O3S
Mol. Mass.:
385.44
SMILES:
COc1ccc2c(C)nc(N=C(N)NS(=O)(=O)c3ccc(C)cc3)nc2c1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: