Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47656
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
3138±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47656
Synonyms:
3-(2-chlorobenzyl)-4-imino-6,7-dimethoxy-3,4-dihydro-2(1H)-quinazolinethione | 4-amino-3-(2-chlorobenzyl)-6,7-dimethoxy-quinazoline-2-thione | 4-amino-3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-2-quinazolinethione | 4-amino-3-[(2-chlorophenyl)methyl]-6,7-dimethoxyquinazoline-2-thione | 4-azanyl-3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-quinazoline-2-thione | MLS000763996 | SMR000336150 | cid_1481748
Type:
Small organic molecule
Emp. Form.:
C17H16ClN3O2S
Mol. Mass.:
361.846
SMILES:
COc1cc2nc(=S)n(Cc3ccccc3Cl)c(N)c2cc1OC
Structure:
Search PDB for entries with ligand similarity: