Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47657
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
2762±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47657
Synonyms:
(4-methoxyphenyl)-[(E)-2-[6-methyl-3-(methylthio)-1,2,4-triazin-5-yl]vinyl]amine | 4-methoxy-N-[(E)-2-(6-methyl-3-methylsulfanyl-1,2,4-triazin-5-yl)ethenyl]aniline | 4-methoxy-N-[(E)-2-[6-methyl-3-(methylthio)-1,2,4-triazin-5-yl]ethenyl]aniline | MLS000707050 | N-(4-methoxyphenyl)-N-{2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]vinyl}amine | SMR000334447 | cid_6409765
Type:
Small organic molecule
Emp. Form.:
C14H16N4OS
Mol. Mass.:
288.368
SMILES:
COc1ccc(cc1)N=CCc1nc(SC)nnc1C |w:8.8|
Structure:
Search PDB for entries with ligand similarity: