Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 8
Ligand
BDBM47763
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47763
Synonyms:
1-(4-chloranyl-2,5-dimethoxy-phenyl)sulfonyl-2-ethyl-imidazole | 1-(4-chloro-2,5-dimethoxy-phenyl)sulfonyl-2-ethyl-imidazole | 1-(4-chloro-2,5-dimethoxyphenyl)sulfonyl-2-ethylimidazole | 1-[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-2-ethyl-1H-imidazole | MLS000705517 | SMR000231827 | cid_850092
Type:
Small organic molecule
Emp. Form.:
C13H15ClN2O4S
Mol. Mass.:
330.787
SMILES:
CCc1nccn1S(=O)(=O)c1cc(OC)c(Cl)cc1OC
Structure:
Search PDB for entries with ligand similarity: