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Target
Regulator of G-protein signaling 8
Ligand
BDBM47765
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47765
Synonyms:
MLS000677175 | N-(dibenzylcarbamothioyl)-2-methylpropanamide | N-(dibenzylthiocarbamoyl)-2-methyl-propionamide | N-[(dibenzylamino)carbonothioyl]-2-methylpropanamide | N-[[bis(phenylmethyl)amino]-sulfanylidenemethyl]-2-methylpropanamide | N-[bis(phenylmethyl)carbamothioyl]-2-methyl-propanamide | SMR000270987 | cid_801325
Type:
Small organic molecule
Emp. Form.:
C19H22N2OS
Mol. Mass.:
326.456
SMILES:
CC(C)C(=O)NC(=S)N(Cc1ccccc1)Cc1ccccc1
Structure:
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