Target
Regulator of G-protein signaling 8
Ligand
BDBM47771
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47771
Synonyms:
2-[(2-methylsulfanylphenyl)carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid | 2-[[2-(methylthio)anilino]-oxomethyl]-3-bicyclo[2.2.1]heptanecarboxylic acid | 3-({[2-(methylthio)phenyl]amino}carbonyl)bicyclo[2.2.1]heptane-2-carboxylic acid | 3-[[2-(methylthio)phenyl]carbamoyl]norbornane-2-carboxylic acid | MLS000663283 | SMR000301317 | cid_4671471
Type:
Small organic molecule
Emp. Form.:
C16H19NO3S
Mol. Mass.:
305.392
SMILES:
[H]C12CCC([H])(C1)C(C2C(O)=O)C(=O)Nc1ccccc1SC |TLB:12:7:6:3.2,THB:9:8:6:3.2|
Structure:
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